Advanced Research Projects Agency for Health (Arpa-H)
CFDA 93.384 · Federal Grants & Funding
Total Funding
$1.75B
Awards
145
Recipients
109
States
31
Last Updated
Apr 16, 2026
Yearly Funding Trend
| Fiscal Year | Obligations | Awards | YoY Change |
|---|---|---|---|
| 2024 | $958.8M | 65 | |
| 2025 | $631.7M | 50 | -34.1% |
| 2026 | $156.4M | 30 | -75.2% |
Award Type Mix
| Type | Obligations | Awards |
|---|---|---|
| $0 | 0 | |
| $0 | 0 | |
| $0 | 0 |
Top 50 Awards under CFDA 93.384
Largest individual obligations for Advanced Research Projects Agency for Health (Arpa-H).
| Award | Recipient | Awarding Agency | Place | FY | Obligation |
|---|---|---|---|---|---|
ASST_NON_AY2AX000007_075 REQUEST FOR OTHER TRANSACTION (OT) CONSORTIUM AGREEMENTS (RCA): TWO ARPA-H HUBS & NATIONWIDE NETWORK OF SPOKES | NATIONAL COLLEGIATE INVENTORS & INNOVATORS ALLIANCE, INC. Massachusetts | Department of Health and Human Services National Institutes of Health | MA-90 | 2024 | $128,884,967 |
ASST_NON_AY2AX000005_075 A TRANSFORMATIVE PLATFORM TO COMBAT ANTIBIOTIC RESISTANT BACTERIA | PRESIDENT AND FELLOWS OF HARVARD COLLEGE Massachusetts | Department of Health and Human Services National Institutes of Health | BOSTON, MA-07 | 2024 | $69,867,044 |
ASST_NON_AY1AX000003_075 THOR: TARGETED HYBRID ONCOTHERAPEUTIC REGULATION | WILLIAM MARSH RICE UNIVERSITY Texas | Department of Health and Human Services National Institutes of Health | TX-90 | 2025 | $44,434,908 |
ASST_NON_AY2AX000006_075 MAPPING THE CANCER AND ORGAN DEGRADOME ATLAS (CODA) TO UNLOCK SYNTHETIC BIOMARKERS FOR MULTI-CANCER EARLY DETECTION | GEORGIA TECH RESEARCH CORP Georgia | Department of Health and Human Services National Institutes of Health | ATLANTA, GA-90 | 2024 | $43,005,255 |
ASST_NON_AY2AX000072_075 PERSONALIZED ANALYTICS FOR TRANSFORMING HEALTHCARE (PATH) | BUCK INSTITUTE FOR RESEARCH ON AGING California | Department of Health and Human Services National Institutes of Health | NOVATO, CA-02 | 2025 | $39,341,765 |
ASST_NON_AY2AX000056_075 VIABILITY, IMAGING, SURGICAL, IMMUNOMODULATION, OCULAR PRESERVATION AND NEUROREGENERATION (VISION) STRATEGIES FOR WHOLE EYE TRANSPLANT | THE LELAND STANFORD JUNIOR UNIVERSITY California | Department of Health and Human Services National Institutes of Health | PALO ALTO, CA-16 | 2025 | $35,515,927 |
ASST_NON_AY1AX000039_075 PROTECT AGAINST EMERGENT ALPHAVIRUSES THROUGH COMPUTATION (PEAC) - ALPHAVIRUSES CAUSE NEUROLOGICAL AND RHEUMATIC DISEASES AND POSE SUBSTANTIAL RISKS TO HUMAN HEALTH THROUGH RECURR… | VANDERBILT UNIVERSITY Tennessee | Department of Health and Human Services National Institutes of Health | TN-90 | 2024 | $31,267,375 |
ASST_NON_D24AC00084_014 CELL THERAPIES FOR NEUROINFLAMMATION AND NEURODEGENERATION PROGRAMMABLE PLATFORM FOR TARGETING THERAPIES TO THE BRAIN | REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE California | Department of the Interior Departmental Offices | SAN FRANCISCO, CA-90 | 2024 | $31,110,405 |
ASST_NON_AY1AX000055_075 STRATEGIC HERPESVIRUS IMMUNE EVASION AND LATENCY DEFENSE (SHIELD) | LA JOLLA INSTITUTE FOR IMMUNOLOGY California | Department of Health and Human Services National Institutes of Health | CA-90 | 2024 | $31,104,137 |
ASST_NON_AY1AX000036_075 MACHINE LEARNING-ENABLED DESIGN OF NOROVIRUS AND HERPESVIRUS VACCINES - WE PROPOSE A HIGHLY INTEGRATED AND SYNERGISTIC PROGRAM TO DEVELOP UNIVERSAL VACCINE DESIGN APPROACHES THA… | UNIVERSITY OF WASHINGTON Washington | Department of Health and Human Services National Institutes of Health | WA-90 | 2024 | $29,978,323 |
ASST_NON_AY2AX000076_075 WHEAT-BASED HIGH-EFFICIENCY ENZYME AND API TECHNOLOGY (WHEAT) | GINKGO BIOWORKS, INC. Massachusetts | Department of Health and Human Services National Institutes of Health | MA-90 | 2025 | $29,214,224 |
ASST_NON_AY2AX000054_075 PROJECT A-FAVE: APPLIED BIOTECHNOLOGY FOR BROAD FLAVIVIRUS ANTIGEN DISCOVERY AND VACCINE CANDIDATE EVALUATION | VACCINE COMPANY INC Maryland | Department of Health and Human Services National Institutes of Health | MD-90 | 2024 | $28,179,321 |
ASST_NON_D24AC00040_014 THE PROPOSAL AIMS TO DEVELOP TWO DISTINCT ORALLY INGESTIBLE DEVICES THAT WOULD ENABLE TREATMENTS OF METABOLIC DISEASES THAT CURRENTLY REQUIRE INVASIVE INJECTIONS OR SURGERY. THE F… | MASSACHUSETTS INSTITUTE OF TECHNOLOGY Massachusetts | Department of the Interior Departmental Offices | MA-90 | 2024 | $26,978,959 |
ASST_NON_AY2AX000145_075 PHARMACOLOGICAL RESEARCH AND EVALUATION THROUGH DIGITAL INTEGRATION AND CLINICAL TRIAL SIMULATION (PREDICTS) | DEEP ORIGIN FEDERAL LLC California | Department of Health and Human Services National Institutes of Health | SOUTH SAN FRANCISCO, CA-15 | 2025 | $26,091,750 |
ASST_NON_AY2AX000040_075 YOUR CELLS, YOUR CURE: ULTRA SCALABLE BIOMANUFACTURING OF PERSONALIZED STEM CELLS FOR ALL AMERICANS | CELLINO BIOTECH INC Massachusetts | Department of Health and Human Services National Institutes of Health | MA-90 | 2024 | $24,969,307 |
ASST_NON_AY1AX000001_075 CUREIT: CURING THE UNCURABLE VIA RNA-ENCODED IMMUNOGENE TUNING - MORE THAN 25 MILLION AMERICANS CURRENTLY LIVE WITH AUTOIMMUNE DISEASE, AND ALMOST TWO MILLION ARE PROJECTED TO BE… | EMORY UNIVERSITY Georgia | Department of Health and Human Services National Institutes of Health | GA-90 | 2024 | $24,754,589 |
ASST_NON_AY2AX000074_075 ENGINEERED MONOMERIC IGA NEUTROPHIL-ENGAGERS FOR CANCER | TIGATX INC Massachusetts | Department of Health and Human Services National Institutes of Health | MA-90 | 2025 | $24,411,331 |
ASST_NON_AY2AX000004_075 PLURIPOTENT STEM CELL-DERIVED THYMIC EPITHELIAL CELLS TO RESCUE ATHYMIC PATIENTS AND REVERSE IMMUNOSENESCENCE FROM THYMIC INVOLUTION | THYMMUNE THERAPEUTICS INC Massachusetts | Department of Health and Human Services National Institutes of Health | CAMBRIDGE, MA-07 | 2024 | $24,042,868 |
ASST_NON_AY2AX000042_075 THEIA: TOTAL HUMAN EYE-ALLOTRANSPLANTATION INNOVATION ADVANCEMENT | THE REGENTS OF THE UNIVERSITY OF COLORADO Colorado | Department of Health and Human Services National Institutes of Health | AURORA, CO-06 | 2024 | $23,538,293 |
ASST_NON_AY2AX000065_075 PLATFORM ACCELERATING RURAL ACCESS TO DISTRIBUTED AND INTEGRATED MOBILE CARE (PARADIGM) | SRI INTERNATIONAL California | Department of Health and Human Services National Institutes of Health | MENLO PARK, CA-16 | 2025 | $23,506,440 |
ASST_NON_AY2AX000124_075 CARDIOVERSE: COMPREHENSIVE ASSESSMENT OF CARDIAC RISK THROUGH DATA-DRIVEN IN-SILICO VIRTUAL ECOSYSTEMS FOR SAFETY EVALUATION | JACKSON LABORATORY Maine | Department of Health and Human Services National Institutes of Health | ME-90 | 2025 | $23,169,820 |
ASST_NON_AY2AX000118_075 AN INTEGRATED HUMAN DATA STACK TO UNLOCK THE FUTURE OF IN SILICO LEARNING MODELS | THE CHARLES STARK DRAPER LABORATORY, INC. Massachusetts | Department of Health and Human Services National Institutes of Health | CAMBRIDGE, MA-07 | 2025 | $22,597,264 |
ASST_NON_AY2AX000048_075 NORMOTHERMIC MACHINE PERFUSION (NMP) TO RESCUE DISCARDED HUMAN KIDNEYS BACK INTO THE DONOR TRANSPLANT POOL- NO KIDNEY LEFT BEHIND | 34 LIVES, PUBLIC BENEFIT CORPORATION (PBC) Indiana | Department of Health and Human Services National Institutes of Health | WEST LAFAYETTE, IN-04 | 2024 | $22,381,962 |
ASST_NON_AY2AX000031_075 DISEASE-AGNOSTIC INNATE IMMUNOTHERAPEUTIC RNA PLATFORM | PRESIDENT AND FELLOWS OF HARVARD COLLEGE Massachusetts | Department of Health and Human Services National Institutes of Health | MA-90 | 2024 | $22,010,380 |
ASST_NON_AY2AX000131_075 NEOPLASM EARLY PREDICTION THROUGH USE OF NEOJUNCTION-DERIVATIVES AND ENZYMES (NEPTUNE) | GRAFTON BIOSCIENCES INC. Georgia | Department of Health and Human Services National Institutes of Health | PEACHTREE CORNERS, GA-04 | 2025 | $20,000,784 |
ASST_NON_D24AC00345_014 COLUMBIA AIMS TO REVOLUTIONIZE PHARMACOLOGY BY DELIVERING A HIGH RESOLUTION PRECISION MONITORING SYSTEM THAT CAN BE USED IN LARGE POPULATIONS TO ASSESS DRUG EFFICACY AND IN INDIVI… | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK New York | Department of the Interior Departmental Offices | NY-13 | 2024 | $18,474,445 |
ASST_NON_AY2AX000146_075 DATAMAP: DIGITAL ACCELERATION OF TOXICITY ASSESSMENT WITH MECHANISTIC AND AI-DRIVEN PREDICTION | INDUCTIVE BIO, INC. New York | Department of Health and Human Services National Institutes of Health | BROOKLYN, NY-08 | 2025 | $18,353,569 |
ASST_NON_D25AC00432_014 WE AIM TO DEVELOP A SCALABLE PATIENT SPECIFIC BIOPRINTED LIVER USING IPSCS. THIS LIVERWILL BE TAILORED TO A PATIENTS UNIQUE ANATOMY AND PHYSIOLOGY WITHOUT THE NEED FOR DONOR TISSU… | UNIVERSITY OF CALIFORNIA, SAN DIEGO California | Department of the Interior Departmental Offices | CA-50 | 2025 | $18,332,570 |
ASST_NON_D25AC00460_014 LIVER DISEASE CONSTITUTES AN URGENT PUBLIC HEALTH CHALLENGE BECAUSE UNLIKE MOST OTHER DISEASES DEATHS DUE TO LIVER DISEASE ARE RAPIDLY RISING. THIS INCREASE IS ADDING TO AN ALREAD… | CARNEGIE MELLON UNIVERSITY Pennsylvania | Department of the Interior Departmental Offices | PA-90 | 2025 | $18,054,329 |
ASST_NON_D25AC00322_014 DAMAGE OF A SINGLE ORGAN ACCOUNTS FOR THE MAJORITY OF HUMAN ILLNESSES WITH LIVER DISEASE AFFECTING OVER 500 MILLION PEOPLE AND ACCOUNTING FOR OVER 2 MILLION ANNUAL DEATHS WORLDWID… | PRESIDENT AND FELLOWS OF HARVARD COLLEGE Massachusetts | Department of the Interior Departmental Offices | MA-90 | 2025 | $17,815,284 |
ASST_NON_AY2AX000077_075 AI-ENABLED GENERATION OF ANTIGEN-SPECIFIC ANTIBODIES | VANDERBILT UNIVERSITY MEDICAL CENTER Tennessee | Department of Health and Human Services National Institutes of Health | NASHVILLE, TN-05 | 2025 | $17,258,990 |
ASST_NON_AY1AX000035_075 STRUCTURALLY ENABLING THE "AVOID-OME" TO ACCELERATE DRUG DISCOVERY | REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE California | Department of Health and Human Services National Institutes of Health | SAN FRANCISCO, CA-11 | 2024 | $15,656,995 |
ASST_NON_AY2AX000051_075 PROTECT: PRO/PREBIOTIC REGULATION FOR OPTIMIZED TREATMENT AND ERADICATION OF CLINICAL TRIALS | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE California | Department of Health and Human Services National Institutes of Health | CA-90 | 2024 | $15,546,656 |
ASST_NON_AY2AX000012_075 NOVAJOINT | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK New York | Department of Health and Human Services National Institutes of Health | NEW YORK, NY-13 | 2024 | $15,533,132 |
ASST_NON_AY1AX000002_075 HEALTH ENABLING ADVANCEMENTS THROUGH REGENERATIVE TISSUE PRINTING (HEART) - DESPITE DECADES OF PROMISE, TISSUE ENGINEERING HAS FALLEN FAR SHORT OF PRODUCING HUMAN-SCALE SOLID AND… | THE LELAND STANFORD JUNIOR UNIVERSITY California | Department of Health and Human Services National Institutes of Health | PALO ALTO, CA-16 | 2024 | $15,479,192 |
ASST_NON_AY2AX000133_075 NOVEL APPROACHES TO UNCOVERING CANCER (NEPTUNE) | OWLSTONE MEDICAL LIMITED | Department of Health and Human Services National Institutes of Health | — | 2025 | $15,372,602 |
ASST_NON_AY2AX000013_075 BUD NEXTGENREGEN FOR OA - BUD NEXTGENREGEN FOR OA | DUKE UNIVERSITY North Carolina | Department of Health and Human Services National Institutes of Health | NC-90 | 2024 | $14,933,524 |
ASST_NON_AY1AX000010_075 SPIKES: PROGRAMMABLE SCALABLE THERAPEUTICS FOR IMMUNE-DIRECTED CANCER-KILLING | UNIVERSITY OF MISSOURI SYSTEM Missouri | Department of Health and Human Services National Institutes of Health | COLUMBIA, MO-03 | 2025 | $14,916,821 |
ASST_NON_AY2AX000132_075 PEPTIDE REPORTERS FOR EARLY SENSING OF CANCER BY INTERNALIZATION OF NUCLEIC ACID TEMPLATES (PRESCIENT) | SRI INTERNATIONAL California | Department of Health and Human Services National Institutes of Health | MENLO PARK, CA-16 | 2025 | $14,813,661 |
ASST_NON_D24AC00039_014 THE PROPOSAL AIMS TO DEVELOP A FAST HANDHELD AFFORDABLE OPTICAL COHERENCE TOMOGRAPHY (OCT) DEVICE THE SIZE OF A CAMCORDER THAT WILL BE ABLE TO SCAN THE EYE FASTER THAN CURRENT TIM… | WASHINGTON UNIVERSITY, THE Missouri | Department of the Interior Departmental Offices | MO-01 | 2024 | $14,333,912 |
ASST_NON_D25AC00239_014 THE OBJECTIVE OF THIS PROPOSAL IS TO DEVELOP A VASCULARIZED IMMUNOCOMPETENT TISSUE AS AN ALTERNATIVE LIVER (VITAL). THE TRANSFORMATIVE VITAL LIVER WILL INCLUDE SUTURABLE BLOOD VES… | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER Texas | Department of the Interior Departmental Offices | — | 2025 | $14,330,656 |
ASST_NON_AY1AX000030_075 AGILE AND SCALABLE MANUFACTURING OF THREE-DIMENSIONAL TUMOR MODELS | UNIVERSITY OF ILLINOIS Illinois | Department of Health and Human Services National Institutes of Health | IL-90 | 2024 | $13,798,949 |
ASST_NON_AY2AX000014_075 NITRO-MBMAT | THE REGENTS OF THE UNIVERSITY OF COLORADO Colorado | Department of Health and Human Services National Institutes of Health | BOULDER, CO-02 | 2024 | $13,704,658 |
ASST_NON_D25AC00320_014 HE WAKE FOREST INSTITUTE FOR REGENERATIVE MEDICINE (WFIRM) HAS OVER TWO DECADES OF EXPERIENCE USING A VARIETY OF 3D PRINTING MODALITIES TO DEVELOP IMPLANTABLE HUMAN TISSUE CONSTRU… | WAKE FOREST UNIVERSITY HEALTH SCIENCES North Carolina | Department of the Interior Departmental Offices | NC-05 | 2025 | $13,431,738 |
ASST_NON_D24AC00358_014 SURGICAL REMOVAL OF A TUMOR IS A MAINSTAY TREATMENT FOR MANY CANCER TYPES. HOWEVER BECAUSE THE SURGEON DOES NOT HAVE A REALTIME MICROSCOPIC VIEW OF THE CANCEROUS TISSUE DURING THE… | UNIVERSITY OF ILLINOIS Illinois | Department of the Interior Departmental Offices | IL-13 | 2024 | $13,340,331 |
ASST_NON_AY2AX000154_075 ENABLING ACCESS TO TRANSFORMATIVE THERAPIES THROUGH CONTINUOUS MANUFACTURING OF EXTRACELLULAR VESICLES | LANDMARK BIO, LLC Massachusetts | Department of Health and Human Services National Institutes of Health | WATERTOWN, MA-05 | 2026 | $12,238,047 |
ASST_NON_D24AC00156_014 THIS PROJECT IS AIMED AT DEVELOPING A LOW COST NOVEL DEVICE FOR BREAST MRI. MRI IS A PROVEN MODALITY FOR IMAGING CANCERS OF THE BREAST AND THE PRIMARY FACTOR LIMITING ITS WIDESPRE… | YALE UNIV Connecticut | Department of the Interior Departmental Offices | CT-03 | 2024 | $12,087,876 |
ASST_NON_AY2AX000159_075 RAPAMYCIN + SEMAGLUTIDE TO OPTIMIZE, RESTORE, AND EXTEND HEALTHSPAN (RSTORE-H) | THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO Texas | Department of Health and Human Services National Institutes of Health | SAN ANTONIO, TX-20 | 2026 | $11,904,972 |
ASST_NON_AY2AX000073_075 CLOSING THE DOORS TO ALL PATHOGENS | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI New York | Department of Health and Human Services National Institutes of Health | NY-90 | 2025 | $11,846,606 |
ASST_NON_AY2AX000015_075 THE NITRO CONSORTIUM; JOINT REGENERATION IN OSTEOARTHRITIS | WASHINGTON UNIVERSITY, THE Missouri | Department of Health and Human Services National Institutes of Health | MO-90 | 2024 | $11,741,417 |
Top 50 awards shown, ranked by obligated amount. Dates reflect performance period; last-modified dates match USAspending.gov. Complete listings include all transaction history going back to FY2024.
Spending by State
| State | Funding | Awards |
|---|---|---|
| Massachusetts | $474.4M | 25 |
| California | $364.9M | 28 |
| New York | $130.8M | 15 |
| Georgia | $108.4M | 6 |
| Texas | $95.8M | 8 |
| Tennessee | $72.4M | 7 |
| Washington | $47.3M | 3 |
| Pennsylvania | $43.9M | 5 |
| North Carolina | $43.4M | 4 |
| Colorado | $43.0M | 3 |
| Maryland | $42.7M | 3 |
| Missouri | $41.0M | 3 |
| Illinois | $37.0M | 3 |
| Indiana | $26.4M | 2 |
| Maine | $23.2M | 1 |
| Connecticut | $15.6M | 2 |
| Ohio | $13.9M | 2 |
| Virginia | $13.6M | 2 |
| Michigan | $10.5M | 1 |
| Louisiana | $10.0M | 1 |
| Florida | $8.4M | 5 |
| New Hampshire | $8.0M | 1 |
| Alabama | $5.6M | 1 |
| Arizona | $5.3M | 2 |
| Utah | $4.0M | 1 |
| Minnesota | $3.7M | 1 |
| Delaware | $3.1M | 1 |
| Arkansas | $3.0M | 1 |
| District of Columbia | $2.7M | 1 |
| New Jersey | $1.3M | 1 |
| Wisconsin | $1.1M | 1 |
Top Recipients
Agencies Administering This Program
Source: USAspending.gov · All Programs